# Evaluation of the Protective Efficacy of TV003 or Previous Zika Infection Against Infection With ZIKV-SJRP Challenge Compared to DENV and ZIKV-naïve Controls Against Infection With ZIKV-SJRP Challenge

> **NCT06805487** · PHASE1 · COMPLETED · sponsor: **National Institute of Allergy and Infectious Diseases (NIAID)** · enrollment: 27 (actual)

## Conditions studied

- Zika Virus

## Interventions

- **BIOLOGICAL:** TetraVax-DV-TV003 (TV003)
- **BIOLOGICAL:** Plasmalyte
- **BIOLOGICAL:** Challenge virus ZIKV-SJRP/2016-184

## Key facts

- **NCT ID:** NCT06805487
- **Lead sponsor:** National Institute of Allergy and Infectious Diseases (NIAID)
- **Sponsor class:** NIH
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2024-09-24
- **Primary completion:** 2025-09-15
- **Final completion:** 2025-09-15
- **Target enrollment:** 27 (ACTUAL)
- **Last updated:** 2026-03-09

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06805487

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06805487, "Evaluation of the Protective Efficacy of TV003 or Previous Zika Infection Against Infection With ZIKV-SJRP Challenge Compared to DENV and ZIKV-naïve Controls Against Infection With ZIKV-SJRP Challenge". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT06805487. Licensed CC0.

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