# Pain Control and Quality of Recovery After Intravenous Methadone Versus Intravenous Remifentanil in Craniotomy Surgery

> **NCT06810336** · EARLY_PHASE1 · RECRUITING · sponsor: **University of Virginia** · enrollment: 40 (estimated)

## Conditions studied

- Brain Injury
- Brain Tumors
- Craniotomy Surgery
- Pain
- Postoperative
- Postoperative Care

## Interventions

- **DRUG:** Remifentanil
- **DRUG:** Methadone

## Key facts

- **NCT ID:** NCT06810336
- **Lead sponsor:** University of Virginia
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-03-10
- **Primary completion:** 2027-09-10
- **Final completion:** 2027-09-10
- **Target enrollment:** 40 (ESTIMATED)
- **Last updated:** 2026-05-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06810336

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06810336, "Pain Control and Quality of Recovery After Intravenous Methadone Versus Intravenous Remifentanil in Craniotomy Surgery". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT06810336. Licensed CC0.

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