# A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

> **NCT06819878** · PHASE3 · RECRUITING · sponsor: **Hoffmann-La Roche** · enrollment: 600 (estimated)

## Conditions studied

- Moderately to Severely Active Crohns Disease

## Interventions

- **DRUG:** Afimkibart
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT06819878
- **Lead sponsor:** Hoffmann-La Roche
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-03-17
- **Primary completion:** 2028-12-31
- **Final completion:** 2033-12-31
- **Target enrollment:** 600 (ESTIMATED)
- **Last updated:** 2026-05-04

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06819878

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06819878, "A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease". Retrieved via AI Analytics 2026-06-15 from https://api.ai-analytics.org/clinical/NCT06819878. Licensed CC0.

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