# Melatonin Effects on Cardiovascular Disease Mechanisms in Midlife Women: A Randomized Clinical Trial

> **NCT06826755** · NA · RECRUITING · sponsor: **Mayo Clinic** · enrollment: 70 (estimated)

## Conditions studied

- Perimenopause
- Hypertension

## Interventions

- **DIETARY_SUPPLEMENT:** Terry Naturally® melatonin 5mg SR
- **DIETARY_SUPPLEMENT:** Placebo

## Key facts

- **NCT ID:** NCT06826755
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-05-23
- **Primary completion:** 2026-09
- **Final completion:** 2027-01
- **Target enrollment:** 70 (ESTIMATED)
- **Last updated:** 2025-11-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06826755

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06826755, "Melatonin Effects on Cardiovascular Disease Mechanisms in Midlife Women: A Randomized Clinical Trial". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT06826755. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*