# Laser Treatment with Methylene Blue Vs. Nanoparticle-Assisted Photodynamic Therapy for Gingival Pigmentation: a Randomized Clinical Trial

> **NCT06834087** · NA · ENROLLING_BY_INVITATION · sponsor: **Roaa Hadi Hussein Jasem** · enrollment: 45 (estimated)

## Conditions studied

- Physiological Gingival Pigmentation

## Interventions

- **PROCEDURE:** Laser-Assisted Gingival Depigmentation
- **DRUG:** Photodynamic Therapy with Conventional Methylene Blue
- **DRUG:** Photodynamic Therapy with Methylene Blue Nanoparticles

## Key facts

- **NCT ID:** NCT06834087
- **Lead sponsor:** Roaa Hadi Hussein Jasem
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ENROLLING_BY_INVITATION
- **Start date:** 2025-03-15
- **Primary completion:** 2025-09-14
- **Final completion:** 2025-11-15
- **Target enrollment:** 45 (ESTIMATED)
- **Last updated:** 2025-02-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06834087

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06834087, "Laser Treatment with Methylene Blue Vs. Nanoparticle-Assisted Photodynamic Therapy for Gingival Pigmentation: a Randomized Clinical Trial". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT06834087. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*