Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell Therapy
Conditions
- Large B-Cell Lymphoma With IRF4 Rearrangement
- Recurrent Aggressive B-Cell Non-Hodgkin Lymphoma
- Recurrent ALK-Positive Large B-Cell Lymphoma
- Recurrent Diffuse Large B-Cell Lymphoma Activated B-Cell Type
- Recurrent Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation
- Recurrent Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type
- Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
- Recurrent EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
- Recurrent Grade 3b Follicular Lymphoma
- Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements
- Recurrent High Grade B-Cell Lymphoma, Not Otherwise Specified
- Recurrent Intravascular Large B-Cell Lymphoma
- Recurrent Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type
- Recurrent Primary Mediastinal Large B-Cell Lymphoma
- Recurrent T-Cell/Histiocyte-Rich Large B-Cell Lymphoma
- Recurrent Transformed Non-Hodgkin Lymphoma
- Refractory Aggressive B-Cell Non-Hodgkin Lymphoma
- Refractory ALK-Positive Large B-Cell Lymphoma
- Refractory Diffuse Large B-Cell Lymphoma Activated B-Cell Type
- Refractory Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation
- Refractory Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type
- Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
- Refractory EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
- Refractory Grade 3b Follicular Lymphoma
- Refractory High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements
- Refractory High Grade B-Cell Lymphoma, Not Otherwise Specified
- Refractory Intravascular Large B-Cell Lymphoma
- Refractory Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type
- Refractory Primary Mediastinal Large B-Cell Lymphoma
- Refractory T-Cell/Histiocyte-Rich Large B-Cell Lymphoma
- Refractory Transformed Non-Hodgkin Lymphoma
Interventions
- PROCEDURE: Biospecimen Collection
- PROCEDURE: Bone Marrow Aspiration
- PROCEDURE: Bone Marrow Biopsy
- BIOLOGICAL: Chimeric Antigen Receptor T-Cell Therapy
- PROCEDURE: Computed Tomography
- DRUG: Golcadomide
- PROCEDURE: Leukapheresis
- PROCEDURE: Positron Emission Tomography
- BIOLOGICAL: Rituximab
Sponsor
Mayo Clinic