# Duloxetine As an Analgesic in Patients Without Central Sensitivity After Same Sitting Bilateral Total Knee Arthroplasty

> **NCT06837012** · PHASE4 · COMPLETED · sponsor: **Orthopaedic Arthroscopy Knee and Shoulder Clinic** · enrollment: 106 (actual)

## Conditions studied

- Osteoarthritis of Knee
- Central Sensitization
- Central Sensitisation

## Interventions

- **DRUG:** Duloxetine - low dose
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT06837012
- **Lead sponsor:** Orthopaedic Arthroscopy Knee and Shoulder Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-01-01
- **Primary completion:** 2022-07-31
- **Final completion:** 2022-07-31
- **Target enrollment:** 106 (ACTUAL)
- **Last updated:** 2025-02-20

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06837012

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06837012, "Duloxetine As an Analgesic in Patients Without Central Sensitivity After Same Sitting Bilateral Total Knee Arthroplasty". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT06837012. Licensed CC0.

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