# Clinical Trial on 7-day Followed by Maintenance Therapy for 10 Weeks vs. 14-day and no Maintenance Course of Prednisolone for the Treatment of Infantile Epileptic Spasms Syndrome (IESS)

> **NCT06838559** · PHASE4 · ACTIVE_NOT_RECRUITING · sponsor: **University of Colombo** · enrollment: 182 (estimated)

## Conditions studied

- Spasms, Infantile
- Prednisolone

## Interventions

- **DRUG:** Short-Duration Oral Prednisolone with Extended Tapering
- **DRUG:** Standard Oral Prednisolone Regimen with Tapering

## Key facts

- **NCT ID:** NCT06838559
- **Lead sponsor:** University of Colombo
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2025-01-01
- **Primary completion:** 2027-12-31
- **Final completion:** 2027-12-31
- **Target enrollment:** 182 (ESTIMATED)
- **Last updated:** 2025-02-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06838559

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06838559, "Clinical Trial on 7-day Followed by Maintenance Therapy for 10 Weeks vs. 14-day and no Maintenance Course of Prednisolone for the Treatment of Infantile Epileptic Spasms Syndrome (IESS)". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06838559. Licensed CC0.

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