# CRYoablation for Small Tumors As Local Treatment - SIX Trial

> **NCT06839001** · PHASE3 · RECRUITING · sponsor: **Hospital do Coracao** · enrollment: 750 (estimated)

## Conditions studied

- Breast Cancer
- Breast Neoplasm

## Interventions

- **PROCEDURE:** cryoablation
- **PROCEDURE:** Breast Surgery (Lumpectomy or Mastectomy)

## Key facts

- **NCT ID:** NCT06839001
- **Lead sponsor:** Hospital do Coracao
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-03-01
- **Primary completion:** 2027-03-01
- **Final completion:** 2030-03-01
- **Target enrollment:** 750 (ESTIMATED)
- **Last updated:** 2025-06-26


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06839001

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06839001, "CRYoablation for Small Tumors As Local Treatment - SIX Trial". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT06839001. Licensed CC0.

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