Assessment of the PEEP Responsiveness to Titrate End-expiratory Pressure and of the Need for Muscle Relaxation During Prone Positioning in Moderate-to-severe Acute Respiratory Distress Syndrome: A Master Protocol

Conditions

• Acute Respiratory Distress Syndrome (ARDS)
• Intensive Care Units (ICUs)

Interventions

• OTHER: Minimal distension
• OTHER: Maximal Recruitment
• OTHER: Prone position + early NMBAs
• OTHER: Prone position + rescue NMBAs

Sponsor

Assistance Publique - Hôpitaux de Paris