# JOULE - Metabolic Adaptation to Weight Loss in Response to a Behavioural Lifestyle Program With or Without Semaglutide in Adolescents With Obesity

> **NCT06852391** · PHASE4 · RECRUITING · sponsor: **McMaster University** · enrollment: 74 (estimated)

## Conditions studied

- Obesity (Disorder)

## Interventions

- **DRUG:** Semaglutide Pen Injector
- **BEHAVIORAL:** Behavioural Lifestyle Program (BLP)

## Key facts

- **NCT ID:** NCT06852391
- **Lead sponsor:** McMaster University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-06-18
- **Primary completion:** 2027-12-31
- **Final completion:** 2027-12-31
- **Target enrollment:** 74 (ESTIMATED)
- **Last updated:** 2026-01-14

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06852391

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06852391, "JOULE - Metabolic Adaptation to Weight Loss in Response to a Behavioural Lifestyle Program With or Without Semaglutide in Adolescents With Obesity". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06852391. Licensed CC0.

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