# Chemoimmunotherapy With or Without SBRT Before Surgery for Locally Advanced Oral and Oropharyngeal Cancer

> **NCT06861712** · PHASE2 · NOT_YET_RECRUITING · sponsor: **Sun Yat-sen University** · enrollment: 50 (estimated)

## Conditions studied

- Oral Squamous Cell Carcinoma (OSCC)
- Oropharyngeal Squamous Cell Carcinoma (SCC)
- Stereotactic Body Radiation Therapy (SBRT)

## Interventions

- **RADIATION:** SBRT
- **DRUG:** Docetaxel, Cisplatin, Toripalimab
- **PROCEDURE:** Radical resection surgery
- **RADIATION:** IMRT ± chemotherapy/toripalimab

## Key facts

- **NCT ID:** NCT06861712
- **Lead sponsor:** Sun Yat-sen University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-05-06
- **Primary completion:** 2025-12-31
- **Final completion:** 2026-12-31
- **Target enrollment:** 50 (ESTIMATED)
- **Last updated:** 2025-04-25

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06861712

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06861712, "Chemoimmunotherapy With or Without SBRT Before Surgery for Locally Advanced Oral and Oropharyngeal Cancer". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06861712. Licensed CC0.

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