# Pain Perception During Intra-Articular Knee Joint Injection: What is the Effect of Needle Gauge and the Use of Ethyl Chloride?

> **NCT06865170** · PHASE4 · NOT_YET_RECRUITING · sponsor: **University of California, Davis** · enrollment: 88 (estimated)

## Conditions studied

- Osteoarthritis (OA) of the Knee
- Fear of Needles

## Interventions

- **PROCEDURE:** 25 gauge needle
- **PROCEDURE:** 22 gauge needle
- **PROCEDURE:** +/- Ethyl Chloride Topical Aerosol Anesthetic

## Key facts

- **NCT ID:** NCT06865170
- **Lead sponsor:** University of California, Davis
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-05
- **Primary completion:** 2026-05
- **Final completion:** 2026-05
- **Target enrollment:** 88 (ESTIMATED)
- **Last updated:** 2026-01-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06865170

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06865170, "Pain Perception During Intra-Articular Knee Joint Injection: What is the Effect of Needle Gauge and the Use of Ethyl Chloride?". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06865170. Licensed CC0.

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