# A Study of LCAR-AIO CAR-T Cells for Treating Relapsed/Refractory Neurological Autoimmune Diseases

> **NCT06869278** · PHASE1 · RECRUITING · sponsor: **Union Hospital, Tongji Medical College, Huazhong University of Science and Technology** · enrollment: 37 (estimated)

## Conditions studied

- Multiple Sclerosis (MS)
- Neuromyelitis Optica Spectrum Disease (NMOSD)
- Anti-Myelin Oligodendrocyte Glycoprotein-IgG Associated Disorders (MOGAD)
- Myasthenia Gravis

## Interventions

- **BIOLOGICAL:** LCAR-AIO T cells

## Key facts

- **NCT ID:** NCT06869278
- **Lead sponsor:** Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-06-17
- **Primary completion:** 2026-06-30
- **Final completion:** 2029-12-31
- **Target enrollment:** 37 (ESTIMATED)
- **Last updated:** 2025-06-11

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06869278

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06869278, "A Study of LCAR-AIO CAR-T Cells for Treating Relapsed/Refractory Neurological Autoimmune Diseases". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT06869278. Licensed CC0.

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