# Study of EN-374 Gene Therapy in Participants With X-Linked Chronic Granulomatous Disease

> **NCT06876363** · PHASE1,PHASE2 · RECRUITING · sponsor: **Ensoma** · enrollment: 15 (estimated)

## Conditions studied

- X-Linked Chronic Granulomatous Disease

## Interventions

- **GENETIC:** EN-374

## Key facts

- **NCT ID:** NCT06876363
- **Lead sponsor:** Ensoma
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-08-05
- **Primary completion:** 2027-12
- **Final completion:** 2027-12
- **Target enrollment:** 15 (ESTIMATED)
- **Last updated:** 2026-04-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06876363

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06876363, "Study of EN-374 Gene Therapy in Participants With X-Linked Chronic Granulomatous Disease". Retrieved via AI Analytics 2026-06-30 from https://api.ai-analytics.org/clinical/NCT06876363. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
