# Efficacy of Dexmedetomidine Versus Midazolam Sedation on Extubation Time in Mechanically Ventilated Preterm Infants

> **NCT06878703** · PHASE3 · RECRUITING · sponsor: **Assistance Publique - Hôpitaux de Paris** · enrollment: 380 (estimated)

## Conditions studied

- PreTerm Neonate
- Sedation for Invasive Mechanical Ventilation
- Very Preterm Neonates With Sedation for Invasive Mechanical Ventilation

## Interventions

- **DRUG:** Midazolam
- **DRUG:** Dexmedetomidine

## Key facts

- **NCT ID:** NCT06878703
- **Lead sponsor:** Assistance Publique - Hôpitaux de Paris
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-10-16
- **Primary completion:** 2027-12-30
- **Final completion:** 2029-10-16
- **Target enrollment:** 380 (ESTIMATED)
- **Last updated:** 2026-02-10

## Collaborators

- DrData

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06878703

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06878703, "Efficacy of Dexmedetomidine Versus Midazolam Sedation on Extubation Time in Mechanically Ventilated Preterm Infants". Retrieved via AI Analytics 2026-07-29 from https://api.ai-analytics.org/clinical/NCT06878703. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*