Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma

NCT06896110 · clinicaltrials.gov ↗

PHASE1

Phase

ENROLLING_BY_INVITATION

Status

34

Enrollment

OTHER

Sponsor class

Conditions

Glioblastoma (GBM)
Diffuse Midline Glioma (DMG)
Astrocytoma, IDH-Mutant, Grade 4
Diffuse Hemispheric Glioma, H3 G34-Mutant
Gliosarcoma of Brain

Interventions

DRUG: Nivolumab
DRUG: Azacitidine (AZA)
PROCEDURE: lumbar puncture
DIAGNOSTIC_TEST: MRI Contrast

Sponsor

Andrew P. Groves