# Effects of Esketamine on the Incidence of Postoperative Delirium and Postoperative Sleep Disturbance in Elderly Patients After Major Non-cardiac Surgery

> **NCT06900205** · NA · WITHDRAWN · sponsor: **RenJi Hospital**

## Conditions studied

- Postoperative Delirium (POD)
- Postoperative Sleep Disturbance

## Interventions

- **DRUG:** Esketamine
- **DRUG:** 0.9 % saline

## Key facts

- **NCT ID:** NCT06900205
- **Lead sponsor:** RenJi Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2025-04-01
- **Primary completion:** 2026-03-30
- **Final completion:** 2026-09-30
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** The trial protocol has undergone substantial revisions, including modifications to the primary outcome measure, which fundamentally alter the original study objectives. As these changes are not compatible with the initial registration, we
- **Last updated:** 2025-05-16

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06900205

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06900205, "Effects of Esketamine on the Incidence of Postoperative Delirium and Postoperative Sleep Disturbance in Elderly Patients After Major Non-cardiac Surgery". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT06900205. Licensed CC0.

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