# A Phase 4, Randomised Vaccination Study in Healthy Adults to Investigate the Effects of Acellular Pertussis Vaccine on Colonisation With Bordetella Pertussis Using Controlled Human Infection

> **NCT06903221** · PHASE4 · ACTIVE_NOT_RECRUITING · sponsor: **Dimitri Diavatopoulos** · enrollment: 99 (estimated)

## Conditions studied

- Pertussis Infection
- Pertussis Vaccines

## Interventions

- **DRUG:** Tdap-IPV
- **DRUG:** Td-IPV

## Key facts

- **NCT ID:** NCT06903221
- **Lead sponsor:** Dimitri Diavatopoulos
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2024-10-16
- **Primary completion:** 2026-10
- **Final completion:** 2027-04
- **Target enrollment:** 99 (ESTIMATED)
- **Last updated:** 2026-05-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06903221

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06903221, "A Phase 4, Randomised Vaccination Study in Healthy Adults to Investigate the Effects of Acellular Pertussis Vaccine on Colonisation With Bordetella Pertussis Using Controlled Human Infection". Retrieved via AI Analytics 2026-07-21 from https://api.ai-analytics.org/clinical/NCT06903221. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*