# Non Steroidal Anti-inflammatory Drugs in the Prevention of Bone Pain Flares After Palliative Radiotherapy

> **NCT06903585** · PHASE2 · NOT_YET_RECRUITING · sponsor: **American University of Beirut Medical Center** · enrollment: 385 (estimated)

## Conditions studied

- Bone Pain Flare
- Bone Metastasis

## Interventions

- **DRUG:** Naproxen (Proxen S)
- **DRUG:** Placebo
- **DRUG:** Esomeprazole 20mg once daily

## Key facts

- **NCT ID:** NCT06903585
- **Lead sponsor:** American University of Beirut Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-04
- **Primary completion:** 2029-04
- **Final completion:** 2029-04
- **Target enrollment:** 385 (ESTIMATED)
- **Last updated:** 2025-04-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06903585

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06903585, "Non Steroidal Anti-inflammatory Drugs in the Prevention of Bone Pain Flares After Palliative Radiotherapy". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT06903585. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*