Epcoritamab Plus Standard of Care Platinum-Based Chemotherapy and Autologous Hematopoietic Cell Transplant for the Treatment of Relapsed or Refractory Large B-cell Lymphoma
Conditions
- Recurrent Diffuse Large B-Cell Lymphoma
- Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
- Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements
- Recurrent High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements
- Recurrent High Grade B-Cell Lymphoma, Not Otherwise Specified
- Recurrent Nodal Marginal Zone Lymphoma
- Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma
- Refractory Diffuse Large B-Cell Lymphoma
- Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
- Refractory High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements
- Refractory High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements
- Refractory High Grade B-Cell Lymphoma, Not Otherwise Specified
- Refractory Nodal Marginal Zone Lymphoma
- Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions
- PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation
- DRUG: Carboplatin
- DRUG: Cytarabine
- DRUG: Dexamethasone
- BIOLOGICAL: Epcoritamab
- DRUG: Etoposide Phosphate
- DRUG: Gemcitabine
- DRUG: Ifosfamide
- PROCEDURE: Multigated Acquisition Scan
- DRUG: Oxaliplatin
- BIOLOGICAL: Rituximab
Sponsor
Joseph Tuscano
Collaborators