# Preterm Rupture of Membranes Optimising Antibiotics Trial

> **NCT06906757** · NA · NOT_YET_RECRUITING · sponsor: **University of Melbourne** · enrollment: 3900 (estimated)

## Conditions studied

- PPROM
- Preterm

## Interventions

- **DRUG:** Erythromycin 250mg + placebo
- **DRUG:** Azithromycin 500mg + placebo
- **DRUG:** Erythromycin 250mg and Amoxicillin 500mg

## Key facts

- **NCT ID:** NCT06906757
- **Lead sponsor:** University of Melbourne
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-09
- **Primary completion:** 2029-12
- **Final completion:** 2050-12
- **Target enrollment:** 3900 (ESTIMATED)
- **Last updated:** 2025-04-02


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06906757

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06906757, "Preterm Rupture of Membranes Optimising Antibiotics Trial". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06906757. Licensed CC0.

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