# Efficacy and Safety of Entacapone Combined With Madopar in the Treatment of Early Parkinson's Disease: An Observational, Multicenter, Case-Control Study

> **NCT06928519** · — · RECRUITING · sponsor: **Yousheng Xiao** · enrollment: 216 (estimated)

## Conditions studied

- Parkinson Disease (PD)

## Interventions

_None listed._

## Key facts

- **NCT ID:** NCT06928519
- **Lead sponsor:** Yousheng Xiao
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2025-06-05
- **Primary completion:** 2027-04-30
- **Final completion:** 2027-06-30
- **Target enrollment:** 216 (ESTIMATED)
- **Last updated:** 2025-06-24

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06928519

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06928519, "Efficacy and Safety of Entacapone Combined With Madopar in the Treatment of Early Parkinson's Disease: An Observational, Multicenter, Case-Control Study". Retrieved via AI Analytics 2026-07-13 from https://api.ai-analytics.org/clinical/NCT06928519. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*