# Evaluation of Polygenic Risk Score for Epithelial OVarian cancEr Risk Prediction: the PROVE Study

> **NCT06935344** · — · RECRUITING · sponsor: **Catholic University of the Sacred Heart** · enrollment: 1300 (estimated)

## Conditions studied

- Ovarian Cancer

## Interventions

- **GENETIC:** Polygenic Risk Score
- **DIAGNOSTIC_TEST:** Biopsy on normal contralateral ovary
- **GENETIC:** Pharmacogenetic profiles
- **DIAGNOSTIC_TEST:** Full-Field Optical Coherence Tomography (FF-OCT), combined with Dynamic Cell Imaging (Van Gogh System) on detecting ovarian cancer lesions from tissue samples

## Key facts

- **NCT ID:** NCT06935344
- **Lead sponsor:** Catholic University of the Sacred Heart
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2025-06-01
- **Primary completion:** 2027-02
- **Final completion:** 2027-05-01
- **Target enrollment:** 1300 (ESTIMATED)
- **Last updated:** 2026-03-03

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06935344

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06935344, "Evaluation of Polygenic Risk Score for Epithelial OVarian cancEr Risk Prediction: the PROVE Study". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06935344. Licensed CC0.

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