# Single-fraction APBI for Early-stage Breast Cancer With Favorable Histological Subtypes (Breast-1F)

> **NCT06946238** · NA · RECRUITING · sponsor: **IRCCS San Raffaele** · enrollment: 311 (estimated)

## Conditions studied

- Breast Cancer

## Interventions

- **RADIATION:** Adjuvant single-fraction accelerated partial breast irradiation

## Key facts

- **NCT ID:** NCT06946238
- **Lead sponsor:** IRCCS San Raffaele
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-07-25
- **Primary completion:** 2029-06-30
- **Final completion:** 2035-06-30
- **Target enrollment:** 311 (ESTIMATED)
- **Last updated:** 2025-12-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06946238

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06946238, "Single-fraction APBI for Early-stage Breast Cancer With Favorable Histological Subtypes (Breast-1F)". Retrieved via AI Analytics 2026-08-17 from https://api.ai-analytics.org/clinical/NCT06946238. Licensed CC0.

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