# Exploration of the Dynamic Changes and Mechanisms of the Immune Microenvironment in Advanced Colorectal Cancer Treated With IBI363 Combination Therapy

> **NCT06946745** · — · RECRUITING · sponsor: **jianming xu** · enrollment: 50 (estimated)

## Conditions studied

- Immunotherapy

## Interventions

- **OTHER:** tissue biopsy

## Key facts

- **NCT ID:** NCT06946745
- **Lead sponsor:** jianming xu
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2024-12-02
- **Primary completion:** 2027-12-31
- **Final completion:** 2028-12-31
- **Target enrollment:** 50 (ESTIMATED)
- **Last updated:** 2025-04-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06946745

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06946745, "Exploration of the Dynamic Changes and Mechanisms of the Immune Microenvironment in Advanced Colorectal Cancer Treated With IBI363 Combination Therapy". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT06946745. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*