# Comparison of TAF and TDF in Preventing Mother-to-Child Transmission of HBV in Pregnancies With High Viral Loads

> **NCT06947356** · NA · RECRUITING · sponsor: **Guangzhou 8th People's Hospital** · enrollment: 210 (estimated)

## Conditions studied

- Hepatitis B

## Interventions

- **DRUG:** TAF group
- **DRUG:** TDF group

## Key facts

- **NCT ID:** NCT06947356
- **Lead sponsor:** Guangzhou 8th People's Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-05-03
- **Primary completion:** 2028-05-01
- **Final completion:** 2028-05-01
- **Target enrollment:** 210 (ESTIMATED)
- **Last updated:** 2025-05-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06947356

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06947356, "Comparison of TAF and TDF in Preventing Mother-to-Child Transmission of HBV in Pregnancies With High Viral Loads". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT06947356. Licensed CC0.

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