# A Clinical Study to Evaluate the Efficacy and Safety of Envafolimab Combined With Cetuxima-βand mFOLFOX6 in Patients With MSS, RAS/BRAF Wild-Type Metastatic Colorectal Cancer (mCRC)

> **NCT06959693** · PHASE2,PHASE3 · NOT_YET_RECRUITING · sponsor: **Sun Yat-sen University** · enrollment: 590 (estimated)

## Conditions studied

- Metastatic Colorectal Cancer (CRC)

## Interventions

- **DRUG:** Cetuxima-β
- **DRUG:** Envafolimab
- **DRUG:** mFOLFOX6

## Key facts

- **NCT ID:** NCT06959693
- **Lead sponsor:** Sun Yat-sen University
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-06-01
- **Primary completion:** 2028-09-30
- **Final completion:** 2030-06-30
- **Target enrollment:** 590 (ESTIMATED)
- **Last updated:** 2025-05-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06959693

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06959693, "A Clinical Study to Evaluate the Efficacy and Safety of Envafolimab Combined With Cetuxima-βand mFOLFOX6 in Patients With MSS, RAS/BRAF Wild-Type Metastatic Colorectal Cancer (mCRC)". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06959693. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*