# Efficacy of Repeated Transcranial Magnetic Stimulation Combined With a Live Probiotic Tablet (Combined Bifidobacterium, Lactobacillus, Enterococcus and Bacillus Cereus Tablets, Live) in Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)

> **NCT06960369** · PHASE1 · RECRUITING · sponsor: **The First Affiliated Hospital of Soochow University** · enrollment: 400 (estimated)

## Conditions studied

- Irritable Bowel Syndrome
- Irritable Bowel Syndrome With Diarrhea (IBS-D)
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Probiotic
- Chronic Diarrhea
- Intestinal Flora

## Interventions

- **COMBINATION_PRODUCT:** rTMS combined with Live Probiotic tablet
- **DEVICE:** rTMS combined placebo
- **DRUG:** shamrTMS combined with Live Probiotic tablet
- **OTHER:** shamrTMS combined placebo group

## Key facts

- **NCT ID:** NCT06960369
- **Lead sponsor:** The First Affiliated Hospital of Soochow University
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-12-01
- **Primary completion:** 2026-06-01
- **Final completion:** 2026-06-01
- **Target enrollment:** 400 (ESTIMATED)
- **Last updated:** 2025-05-07

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06960369

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06960369, "Efficacy of Repeated Transcranial Magnetic Stimulation Combined With a Live Probiotic Tablet (Combined Bifidobacterium, Lactobacillus, Enterococcus and Bacillus Cereus Tablets, Live) in Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT06960369. Licensed CC0.

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