# Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator

> **NCT06964464** · PHASE4 · RECRUITING · sponsor: **University of Rochester** · enrollment: 2000 (estimated)

## Conditions studied

- Heart Failure With Reduced Ejection Fraction (HFrEF)
- Sudden Cardiac Death
- Ventricular Arrhythmia
- Implantable Cardioverter Defibrillator (ICD)
- Beta-blocker Therapy
- Cardiomyopathy

## Interventions

- **DRUG:** Metoprolol Succinate
- **DRUG:** Carvedilol

## Key facts

- **NCT ID:** NCT06964464
- **Lead sponsor:** University of Rochester
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-08-17
- **Primary completion:** 2031-06-01
- **Final completion:** 2031-07-01
- **Target enrollment:** 2000 (ESTIMATED)
- **Last updated:** 2025-09-18

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06964464

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06964464, "Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT06964464. Licensed CC0.

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