Autologous CAR T Cells Targeting GPC3 (RPCAR01) for the Treatment of Advanced or Metastatic GPC3 Expressing Hepatocellular Carcinoma

NCT06968195 · clinicaltrials.gov ↗

PHASE1

Phase

SUSPENDED

Status

24

Enrollment

OTHER

Sponsor class

Stopped awaiting agreement with Sponsor

Conditions

Advanced Hepatocellular Carcinoma
Metastatic Hepatocellular Carcinoma
Recurrent Hepatocellular Carcinoma
Refractory Hepatocellular Carcinoma
Stage III Hepatocellular Carcinoma AJCC v8
Stage IV Hepatocellular Carcinoma AJCC v8

Interventions

BIOLOGICAL: Anti-GPC3-CAR Autologous T Lymphocytes
PROCEDURE: Biospecimen Collection
PROCEDURE: Computed Tomography
DRUG: Cyclophosphamide
PROCEDURE: Echocardiography Test
DRUG: Fludarabine
PROCEDURE: Leukapheresis
PROCEDURE: Magnetic Resonance Imaging
PROCEDURE: Multigated Acquisition Scan

Sponsor

Roswell Park Cancer Institute