# Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study

> **NCT06972056** · PHASE4 · RECRUITING · sponsor: **Mayo Clinic** · enrollment: 1335 (estimated)

## Conditions studied

- Migraine

## Interventions

- **DRUG:** Atogepant 60 mg
- **DRUG:** Propranolol 160 mg
- **DRUG:** Topiramate 100 mg

## Key facts

- **NCT ID:** NCT06972056
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-07-09
- **Primary completion:** 2029-03-01
- **Final completion:** 2029-12-01
- **Target enrollment:** 1335 (ESTIMATED)
- **Last updated:** 2026-04-03

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06972056

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06972056, "Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT06972056. Licensed CC0.

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