# Natural History of Familial Cerebral Cavernous Malformations: the CCM_Italia Cohort Study

> **NCT06983132** · — · RECRUITING · sponsor: **Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico** · enrollment: 100 (estimated)

## Conditions studied

- CCM
- Familial Cerebral Cavernous Malformation

## Interventions

- **DIAGNOSTIC_TEST:** Cerebral imaging (MRI) according to a dedicated protocol with central MRI reading
- **DIAGNOSTIC_TEST:** Determination of circulating biomarkers

## Key facts

- **NCT ID:** NCT06983132
- **Lead sponsor:** Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2024-11-18
- **Primary completion:** 2027-02-28
- **Final completion:** 2027-02-28
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2025-05-21

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06983132

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06983132, "Natural History of Familial Cerebral Cavernous Malformations: the CCM_Italia Cohort Study". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT06983132. Licensed CC0.

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