# A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive Crisis

> **NCT06989567** · PHASE3 · NOT_YET_RECRUITING · sponsor: **Asklepion Pharmaceuticals, LLC** · enrollment: 120 (estimated)

## Conditions studied

- Sickle Cell Disease

## Interventions

- **DRUG:** L-citrulline
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT06989567
- **Lead sponsor:** Asklepion Pharmaceuticals, LLC
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-07-25
- **Primary completion:** 2027-06
- **Final completion:** 2029-06
- **Target enrollment:** 120 (ESTIMATED)
- **Last updated:** 2025-05-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06989567

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06989567, "A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive Crisis". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT06989567. Licensed CC0.

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