# Efficacy of HFNC Combined With Sequential NIV in Patients With COPD Complicated With Type II Respiratory Failure

> **NCT06992479** · NA · COMPLETED · sponsor: **Beijing YouAn Hospital** · enrollment: 100 (actual)

## Conditions studied

- Chronic Obstructive Pulmonary Disease (COPD)
- Nasal High Flow Oxygen Therapy
- Noninvasive Ventilation
- Respiratory Failure

## Interventions

- **DEVICE:** high-flow nasal cannula oxygen therapy (HFNC) combined with sequential non-invasive ventilation (NIV)
- **DEVICE:** NIV routine treatment

## Key facts

- **NCT ID:** NCT06992479
- **Lead sponsor:** Beijing YouAn Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-01-01
- **Primary completion:** 2024-01-01
- **Final completion:** 2024-01-31
- **Target enrollment:** 100 (ACTUAL)
- **Last updated:** 2025-05-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06992479

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06992479, "Efficacy of HFNC Combined With Sequential NIV in Patients With COPD Complicated With Type II Respiratory Failure". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT06992479. Licensed CC0.

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