# Phase I Trial of QH-1A Hybrid Bio-Artificial Liver With Ex Vivo Blood-Purifying MSCs in Acute-on-Chronic Liver Failure

> **NCT06996392** · PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **Third Affiliated Hospital, Sun Yat-Sen University** · enrollment: 15 (estimated)

## Conditions studied

- Acute-On-Chronic Liver Failure

## Interventions

- **COMBINATION_PRODUCT:** Combining the QH-1A bioartificial liver device with mesenchymal stem cells for blood purification（4 hours）
- **COMBINATION_PRODUCT:** Combining the QH-1A bioartificial liver device with mesenchymal stem cells for blood purification（6 hours）
- **COMBINATION_PRODUCT:** Combining the QH-1A bioartificial liver device with mesenchymal stem cells for blood purification（8 hours）
- **COMBINATION_PRODUCT:** Combining the QH-1A bioartificial liver device with mesenchymal stem cells for blood purification（Multiple-treatment）

## Key facts

- **NCT ID:** NCT06996392
- **Lead sponsor:** Third Affiliated Hospital, Sun Yat-Sen University
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2025-05-07
- **Primary completion:** 2026-12-31
- **Final completion:** 2026-12-31
- **Target enrollment:** 15 (ESTIMATED)
- **Last updated:** 2025-05-30

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06996392

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06996392, "Phase I Trial of QH-1A Hybrid Bio-Artificial Liver With Ex Vivo Blood-Purifying MSCs in Acute-on-Chronic Liver Failure". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT06996392. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*