Decitabine in Combination With Standard of Care Therapy for the Treatment of Surgically Resectable HPV-Negative Head and Neck Cancer

NCT06997094 · clinicaltrials.gov ↗

PHASE1

Phase

RECRUITING

Status

24

Enrollment

OTHER

Sponsor class

Conditions

Human Papillomavirus-Negative Neck Squamous Cell Carcinoma
Resectable Head and Neck Squamous Cell Carcinoma
Resectable Human Papillomavirus-Independent Head and Neck Mucosal Squamous Cell Carcinoma
HPV-Negative Squamous Cell Carcinoma
Resectable Head and Neck Squamous-cell Carcinoma

Interventions

PROCEDURE: Biospecimen Collection
DRUG: Chemotherapy
DRUG: Decitabine
RADIATION: External Beam Radiation Therapy
OTHER: Questionnaire Administration
PROCEDURE: Surgical Procedure

Sponsor

Mayo Clinic