# Megestrol Acetate in Improving Neoadjuvant Chemotherapy-Related Weight Loss in Locally Advanced CRC

> **NCT06998758** · PHASE3 · RECRUITING · sponsor: **Sixth Affiliated Hospital, Sun Yat-sen University** · enrollment: 60 (estimated)

## Conditions studied

- Neoadjuvant Chemotherapy
- Weight Loss

## Interventions

- **DRUG:** Megestrol Acetate

## Key facts

- **NCT ID:** NCT06998758
- **Lead sponsor:** Sixth Affiliated Hospital, Sun Yat-sen University
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-11-11
- **Primary completion:** 2027-05-10
- **Final completion:** 2028-12-31
- **Target enrollment:** 60 (ESTIMATED)
- **Last updated:** 2025-12-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06998758

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06998758, "Megestrol Acetate in Improving Neoadjuvant Chemotherapy-Related Weight Loss in Locally Advanced CRC". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT06998758. Licensed CC0.

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