# Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging.

> **NCT07004764** · PHASE1 · NOT_YET_RECRUITING · sponsor: **Johns Hopkins University** · enrollment: 15 (estimated)

## Conditions studied

- Achilles Tendon Repairs/Reconstructions
- Pilon Fracture of Tibia
- Tibial Plateau Fracture
- Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar)
- Calcaneus Fractures
- Talus Fracture
- Wound Infection Deep
- Wound Infection Post-Traumatic
- Wound Dehiscence, Surgical

## Interventions

- **DRUG:** Nitroglycerin Ointment 2%

## Key facts

- **NCT ID:** NCT07004764
- **Lead sponsor:** Johns Hopkins University
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-11
- **Primary completion:** 2027-09
- **Final completion:** 2027-12
- **Target enrollment:** 15 (ESTIMATED)
- **Last updated:** 2026-03-31

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07004764

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07004764, "Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging.". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT07004764. Licensed CC0.

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