# Clinical Trials to Evaluate Metformin to Treat Depression in People Living With HIV

> **NCT07007221** · PHASE2 · NOT_YET_RECRUITING · sponsor: **University of Minnesota** · enrollment: 600 (estimated)

## Conditions studied

- Depression
- Hiv

## Interventions

- **DRUG:** Metformin
- **DRUG:** Metformin
- **DRUG:** Metformin
- **OTHER:** Placebo
- **DRUG:** Metformin
- **DRUG:** Fluoxetine
- **DRUG:** Metformin+Fluoxetine
- **OTHER:** double placebo

## Key facts

- **NCT ID:** NCT07007221
- **Lead sponsor:** University of Minnesota
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-07-01
- **Primary completion:** 2030-12-01
- **Final completion:** 2030-12-01
- **Target enrollment:** 600 (ESTIMATED)
- **Last updated:** 2026-01-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07007221

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07007221, "Clinical Trials to Evaluate Metformin to Treat Depression in People Living With HIV". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT07007221. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*