# Adjusted Study Protocol: Within-Subject Paired-Eye Design Comparing Pilocarpine 0.1%, Phentolamine 0.75%, and Combination Therapy for Cyclopentolate Reversal in Children

> **NCT07012512** · NA · NOT_YET_RECRUITING · sponsor: **Mansoura University** · enrollment: 60 (estimated)

## Conditions studied

- Pupillary Constriction
- Accomodation

## Interventions

- **DRUG:** Use of phentolamine eye drops to reverse cycloplegia
- **DRUG:** Pilocarpine 0.1%
- **DRUG:** Combination of pilocarpine 0.1% and phentolamine 0.75%

## Key facts

- **NCT ID:** NCT07012512
- **Lead sponsor:** Mansoura University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-06-01
- **Primary completion:** 2025-12-01
- **Final completion:** 2025-12-30
- **Target enrollment:** 60 (ESTIMATED)
- **Last updated:** 2025-06-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07012512

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07012512, "Adjusted Study Protocol: Within-Subject Paired-Eye Design Comparing Pilocarpine 0.1%, Phentolamine 0.75%, and Combination Therapy for Cyclopentolate Reversal in Children". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT07012512. Licensed CC0.

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