Neoadjuvant Darolutamide Alone or in Combination With Standard Therapy for Stage II-IIIA, AR+, TNBC

NCT07016399 · clinicaltrials.gov ↗

PHASE2

Phase

RECRUITING

Status

51

Enrollment

OTHER

Sponsor class

Conditions

Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage IIIA Breast Cancer AJCC v8
Triple-Negative Breast Carcinoma

Interventions

PROCEDURE: Biospecimen Collection
PROCEDURE: Breast Biopsy Procedure
DRUG: Carboplatin
DRUG: Cyclophosphamide
DRUG: Darolutamide
DRUG: Doxorubicin
DRUG: Epirubicin
PROCEDURE: Magnetic Resonance Imaging
DRUG: Paclitaxel
BIOLOGICAL: Pembrolizumab
PROCEDURE: Surgical Procedure
PROCEDURE: Ultrasound Imaging

Sponsor

Vandana Abramson

Collaborators

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