# Mechanisms and Targeted Therapy of Airway Basal Cell Dysfunction in Bronchiolitis Obliterans Syndrome

> **NCT07018804** · NA · ENROLLING_BY_INVITATION · sponsor: **Haikou Affiliated Hospital of Central South University Xiangya School of Medicine** · enrollment: 5 (estimated)

## Conditions studied

- Bronchiolitis Obliterans Syndrome (BOS)

## Interventions

- **PROCEDURE:** Bronchoscopic brushing
- **GENETIC:** Single - cell cloning
- **GENETIC:** Cell function identification
- **GENETIC:** Identification of local microenvironmental changes
- **GENETIC:** Gene editing
- **PROCEDURE:** Prevention of ferret airway basal cell transplantation
- **PROCEDURE:** Transplantation treatment of ferret airway basal cells

## Key facts

- **NCT ID:** NCT07018804
- **Lead sponsor:** Haikou Affiliated Hospital of Central South University Xiangya School of Medicine
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ENROLLING_BY_INVITATION
- **Start date:** 2026-01-01
- **Primary completion:** 2027-06-30
- **Final completion:** 2028-06-30
- **Target enrollment:** 5 (ESTIMATED)
- **Last updated:** 2025-06-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07018804

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07018804, "Mechanisms and Targeted Therapy of Airway Basal Cell Dysfunction in Bronchiolitis Obliterans Syndrome". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT07018804. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*