# Is the Combine Prolotherapy More Effective Than the Traditional Prolotherapy in Patients With Temporomandibular Joint Hypermobility?

> **NCT07020455** · PHASE4 · COMPLETED · sponsor: **Karadeniz Technical University** · enrollment: 26 (actual)

## Conditions studied

- Temporomandibular Disorders (TMD)
- Temporomandibular Pain
- Hypermobility Syndrome (Disorder)
- Hypermobility, Joint
- Arthrocentesis
- Prolotherapy

## Interventions

- **DRUG:** prolotherapy solution of 20% dextrose
- **DRUG:** Arthrocentesis with ringer solution

## Key facts

- **NCT ID:** NCT07020455
- **Lead sponsor:** Karadeniz Technical University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-01-01
- **Primary completion:** 2022-01-01
- **Final completion:** 2025-01-01
- **Target enrollment:** 26 (ACTUAL)
- **Last updated:** 2025-06-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07020455

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07020455, "Is the Combine Prolotherapy More Effective Than the Traditional Prolotherapy in Patients With Temporomandibular Joint Hypermobility?". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT07020455. Licensed CC0.

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