# Effect of Arginine- and Glutamine-based Oral Formulations on Salivary Biomarkers and Clinical Severity of Radiation-induced Oral Mucositis in Head and Neck Cancer: A Randomized Controlled Trial

> **NCT07020754** · PHASE2 · COMPLETED · sponsor: **Ain Shams University** · enrollment: 84 (actual)

## Conditions studied

- Radiation Induced Oral Mucositis
- Oral Mucositis
- Oral Mucositis Due to Radiation

## Interventions

- **DIETARY_SUPPLEMENT:** L-arginine Oral Suspension
- **DIETARY_SUPPLEMENT:** L-glutamine Oral Suspension
- **DIETARY_SUPPLEMENT:** Maltodextrin Oral Suspension (Control)

## Key facts

- **NCT ID:** NCT07020754
- **Lead sponsor:** Ain Shams University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2025-04-01
- **Primary completion:** 2026-01-01
- **Final completion:** 2026-01-25
- **Target enrollment:** 84 (ACTUAL)
- **Last updated:** 2026-01-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07020754

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07020754, "Effect of Arginine- and Glutamine-based Oral Formulations on Salivary Biomarkers and Clinical Severity of Radiation-induced Oral Mucositis in Head and Neck Cancer: A Randomized Controlled Trial". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT07020754. Licensed CC0.

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