# Comparative Assessment of Efficacy & Safety of Sacubitril/Valsartan Versus Ramipril in Patients With Renal Dysfunction Hospitalized With Acute Decompensated Heart Failure

> **NCT07023016** · PHASE2,PHASE3 · COMPLETED · sponsor: **National Heart Institute, Egypt** · enrollment: 515 (actual)

## Conditions studied

- Acute Decompensated Heart Failure (ADHF)
- Chronic Kidney Disease (CKD)

## Interventions

- **DRUG:** Sacubitril / Valsartan
- **DRUG:** Ramipril (ACE-inhibitor)

## Key facts

- **NCT ID:** NCT07023016
- **Lead sponsor:** National Heart Institute, Egypt
- **Sponsor class:** OTHER_GOV
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-11-01
- **Primary completion:** 2025-02-28
- **Final completion:** 2025-02-28
- **Target enrollment:** 515 (ACTUAL)
- **Last updated:** 2025-06-22

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07023016

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07023016, "Comparative Assessment of Efficacy & Safety of Sacubitril/Valsartan Versus Ramipril in Patients With Renal Dysfunction Hospitalized With Acute Decompensated Heart Failure". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT07023016. Licensed CC0.

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