# Definitive Proton Radiotherapy Combined With Chemotherapy and Immunotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma: A Phase I Clinical Study

> **NCT07034118** · PHASE1 · NOT_YET_RECRUITING · sponsor: **Anhui Provincial Hospital** · enrollment: 23 (estimated)

## Conditions studied

- Esophageal Carcinoma

## Interventions

- **RADIATION:** Proton radiotherapy
- **DRUG:** Immune Checkpoint Inhibitors

## Key facts

- **NCT ID:** NCT07034118
- **Lead sponsor:** Anhui Provincial Hospital
- **Sponsor class:** OTHER_GOV
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-08-01
- **Primary completion:** 2027-08-31
- **Final completion:** 2028-08-31
- **Target enrollment:** 23 (ESTIMATED)
- **Last updated:** 2025-06-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07034118

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07034118, "Definitive Proton Radiotherapy Combined With Chemotherapy and Immunotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma: A Phase I Clinical Study". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT07034118. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*