# A Study Evaluating the Efficacy of PD-1 Inhibitor Combined With Denosumab and Chemotherapy in Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer Patients With Driver Gene-Negative Status

> **NCT07034391** · PHASE2 · RECRUITING · sponsor: **China Medical University, China** · enrollment: 40 (estimated)

## Conditions studied

- Non-Small Cell Lung Cancer

## Interventions

- **DRUG:** denosumab combined anti-PD-1 inhibitor with chemotherapy

## Key facts

- **NCT ID:** NCT07034391
- **Lead sponsor:** China Medical University, China
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-05-12
- **Primary completion:** 2026-10-31
- **Final completion:** 2027-10-31
- **Target enrollment:** 40 (ESTIMATED)
- **Last updated:** 2025-06-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07034391

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07034391, "A Study Evaluating the Efficacy of PD-1 Inhibitor Combined With Denosumab and Chemotherapy in Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer Patients With Driver Gene-Negative Status". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT07034391. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*