# A Randomized Controlled Trial of Spermidine for the Prevention of Radiation-Induced Xerostomia in Head and Neck Squamous Cell Carcinoma (Including Nasopharyngeal Carcinoma)

> **NCT07035626** · PHASE1,PHASE2 · RECRUITING · sponsor: **West China Hospital** · enrollment: 58 (estimated)

## Conditions studied

- Radiation-induced Xerostomia

## Interventions

- **DRUG:** Spermidine
- **DRUG:** Spermidine simulants

## Key facts

- **NCT ID:** NCT07035626
- **Lead sponsor:** West China Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-06-25
- **Primary completion:** 2026-06-08
- **Final completion:** 2026-06-08
- **Target enrollment:** 58 (ESTIMATED)
- **Last updated:** 2025-06-26


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07035626

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07035626, "A Randomized Controlled Trial of Spermidine for the Prevention of Radiation-Induced Xerostomia in Head and Neck Squamous Cell Carcinoma (Including Nasopharyngeal Carcinoma)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT07035626. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*