# Pharmacokinetics Impact of HRS-8427 on Bupropion and Midazolam in Healthy Subjects

> **NCT07049107** · PHASE1 · COMPLETED · sponsor: **Jiangsu HengRui Medicine Co., Ltd.** · enrollment: 14 (actual)

## Conditions studied

- Health Volunteer

## Interventions

- **DRUG:** HRS-8427

## Key facts

- **NCT ID:** NCT07049107
- **Lead sponsor:** Jiangsu HengRui Medicine Co., Ltd.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2025-06-23
- **Primary completion:** 2025-07-21
- **Final completion:** 2025-07-21
- **Target enrollment:** 14 (ACTUAL)
- **Last updated:** 2026-03-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07049107

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07049107, "Pharmacokinetics Impact of HRS-8427 on Bupropion and Midazolam in Healthy Subjects". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT07049107. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*